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Structure paper

TitleMolecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems.
Journal, issue, pagesNat Commun, Vol. 13, Page 6391-6391, Year 2022
Publish dateOct 25, 2021 (structure data deposition date)
AuthorsZhu, J. / Gao, Y. / Wang, Y. / Zhan, Q. / Feng, H. / Luo, X. / Li, P. / Liu, S. / Hou, H. / Gao, P.
External linksNat Commun / PubMed:36302770
MethodsX-ray diffraction
Resolution2.4 - 2.55 Å
Structure data

PDB-7vru:
Crystal structure of PacII_M1M2S-DNA-SAH complex
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-7vs4:
Crystal structure of PacII_M1M2S-DNA(m6A)-SAH complex
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-HOH:
WATER

Source
  • pseudomonas alcaligenes (bacteria)
  • synthetic construct (others)
KeywordsTRANSFERASE/DNA / Type I R-M system PacII methytransferase m4C and m6A modification complex / BIOSYNTHETIC PROTEIN / TRANSFERASE-DNA complex

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