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TitleBefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases beta cell mass.
Journal, issue, pagesCell Metab., Vol. 34, Page 1779-1791.e9, Year 2022
Publish dateJul 14, 2021 (structure data deposition date)
AuthorsHill, J.H. / Massaquoi, M.S. / Sweeney, E.G. / Wall, E.S. / Jahl, P. / Bell, R. / Kallio, K. / Derrick, D. / Murtaugh, L.C. / Parthasarathy, R. ...Hill, J.H. / Massaquoi, M.S. / Sweeney, E.G. / Wall, E.S. / Jahl, P. / Bell, R. / Kallio, K. / Derrick, D. / Murtaugh, L.C. / Parthasarathy, R. / Remington, S.J. / Round, J.L. / Guillemin, K.
External linksCell Metab. / PubMed:36240759
MethodsX-ray diffraction
Resolution1.27 Å
Structure data

PDB-7rfq:
STRUCTURE OF BACTERIAL SYLF DOMAIN CONTAINING PROTEIN, BETA CELL EXPANSION FACTOR A (BEFA)
Method: X-RAY DIFFRACTION / Resolution: 1.27 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

Source
  • aeromonas veronii (bacteria)
KeywordsSIGNALING PROTEIN / SYLF DOMAIN / BACTERIAL PROTEIN / DEVELOPMENTAL REGULATOR / BETA CELL EXPANSION FACTOR

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