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Structure paper

TitleGPC3-Unc5 receptor complex structure and role in cell migration.
Journal, issue, pagesCell, Vol. 185, Page 3931-3949.e26, Year 2022
Publish dateMar 21, 2022 (structure data deposition date)
AuthorsAkkermans, O. / Delloye-Bourgeois, C. / Peregrina, C. / Carrasquero-Ordaz, M. / Kokolaki, M. / Berbeira-Santana, M. / Chavent, M. / Reynaud, F. / Raj, R. / Agirre, J. ...Akkermans, O. / Delloye-Bourgeois, C. / Peregrina, C. / Carrasquero-Ordaz, M. / Kokolaki, M. / Berbeira-Santana, M. / Chavent, M. / Reynaud, F. / Raj, R. / Agirre, J. / Aksu, M. / White, E.S. / Lowe, E. / Ben Amar, D. / Zaballa, S. / Huo, J. / Pakos, I. / McCubbin, P.T.N. / Comoletti, D. / Owens, R.J. / Robinson, C.V. / Castellani, V. / Del Toro, D. / Seiradake, E.
External linksCell / PubMed:36240740
MethodsX-ray diffraction
Resolution2.58 - 4.6 Å
Structure data

PDB-7za1:
GPC3-Unc5D octamer structure and role in cell migration
Method: X-RAY DIFFRACTION / Resolution: 4.1 Å

PDB-7za2:
GPC3-Unc5D octamer structure and role in cell migration
Method: X-RAY DIFFRACTION / Resolution: 4.6 Å

PDB-7za3:
GPC3-Unc5D octamer structure and role in cell migration
Method: X-RAY DIFFRACTION / Resolution: 4 Å

PDB-7zav:
GPC3-Unc5D octamer structure and role in cell migration
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-7zaw:
GPC3-Unc5D octamer structure and role in cell migration
Method: X-RAY DIFFRACTION / Resolution: 2.58 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-MAN:
alpha-D-mannopyranose

Source
  • rattus norvegicus (Norway rat)
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / Complex / Cell migration / Glycan-Glycan Interaction / Glycoprotein / Migration

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