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TitleModel of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model.
Journal, issue, pagesNucleic Acids Res., Vol. 50, Page 10436-10448, Year 2022
Publish dateMay 24, 2021 (structure data deposition date)
AuthorsHuskova, A. / Dinesh, D.C. / Srb, P. / Boura, E. / Veverka, V. / Silhan, J.
External linksNucleic Acids Res. / PubMed:36155818
MethodsNMR (solution) / X-ray diffraction
Resolution2.28 Å
Structure data

PDB-7omk:
The NMR structure of the Zf-GRF domains from the mouse Endonuclease VIII-LIKE 3 (mNEIL3)
Method: SOLUTION NMR

PDB-7z5a:
Crystal structure of the trapped complex of mouse Endonuclease VIII-LIKE 3 (mNEIL3) and hairpin DNA with 5'overhang
Method: X-RAY DIFFRACTION / Resolution: 2.28 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / Zinc Finger / NEIL3-GRF / DNA repair / DNA damage / Ap-ICL / DNA crosslink repair / NEIL3 / BER

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