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-Structure paper
Title | Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases. |
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Journal, issue, pages | J. Med. Chem., Vol. 65, Page 12933-12955, Year 2022 |
Publish date | Mar 10, 2022 (structure data deposition date) |
Authors | Alhayek, A. / Abdelsamie, A.S. / Schonauer, E. / Camberlein, V. / Hutterer, E. / Posselt, G. / Serwanja, J. / Blochl, C. / Huber, C.G. / Haupenthal, J. ...Alhayek, A. / Abdelsamie, A.S. / Schonauer, E. / Camberlein, V. / Hutterer, E. / Posselt, G. / Serwanja, J. / Blochl, C. / Huber, C.G. / Haupenthal, J. / Brandstetter, H. / Wessler, S. / Hirsch, A.K.H. |
External links | J. Med. Chem. / PubMed:36154055 |
Methods | X-ray diffraction |
Resolution | 1.8 - 1.95 Å |
Structure data | PDB-7z5u: PDB-7zbv: |
Chemicals | ChemComp-ZN: ChemComp-IFW: ChemComp-CA: ChemComp-HOH: ChemComp-ITO: ChemComp-144: |
Source |
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Keywords | HYDROLASE / collagenase / hydroxamate / ColG / inhibitor / complex / diphosphonate |