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-Structure paper
Title | Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development. |
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Journal, issue, pages | Sci Rep, Vol. 12, Page 15715-, Year 2022 |
Publish date | Aug 10, 2023 (structure data deposition date) |
![]() | Page, N. / Wappett, M. / O'Dowd, C.R. / O'Rourke, M. / Gavory, G. / Zhang, L. / Rountree, J.S.S. / Jordan, L. / Barker, O. / Gibson, H. ...Page, N. / Wappett, M. / O'Dowd, C.R. / O'Rourke, M. / Gavory, G. / Zhang, L. / Rountree, J.S.S. / Jordan, L. / Barker, O. / Gibson, H. / Boyd, C. / Feutren-Burton, S. / McLean, E. / Trevitt, G. / Harrison, T. |
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Methods | X-ray diffraction |
Resolution | 2.32 Å |
Structure data | ![]() PDB-8q61: |
Chemicals | ![]() ChemComp-K06: ![]() ChemComp-GOL: ![]() ChemComp-PO4: ![]() ChemComp-MES: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / Protein Kinase Inhibitor Complex |