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Structure paper

TitleStructural basis of 3'-end poly(A) RNA recognition by LARP1.
Journal, issue, pagesNucleic Acids Res., Vol. 50, Page 9534-9547, Year 2022
Publish dateNov 1, 2021 (structure data deposition date)
AuthorsKozlov, G. / Mattijssen, S. / Jiang, J. / Nyandwi, S. / Sprules, T. / Iben, J.R. / Coon, S.L. / Gaidamakov, S. / Noronha, A.M. / Wilds, C.J. ...Kozlov, G. / Mattijssen, S. / Jiang, J. / Nyandwi, S. / Sprules, T. / Iben, J.R. / Coon, S.L. / Gaidamakov, S. / Noronha, A.M. / Wilds, C.J. / Maraia, R.J. / Gehring, K.
External linksNucleic Acids Res. / PubMed:35979957
MethodsX-ray diffraction
Resolution1.15 - 1.65 Å
Structure data

PDB-7soo:
LaM domain of human LARP1
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-7sop:
LaM domain of human LARP1 in complex with AAAUAA RNA
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-7soq:
LaM domain of human LARP1 in complex with AAA RNA
Method: X-RAY DIFFRACTION / Resolution: 1.15 Å

PDB-7sor:
LaM domain of human LARP1 in complex with AAA RNA
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-7sos:
LaM domain of human LARP1 in complex with AAAA RNA
Method: X-RAY DIFFRACTION / Resolution: 1.25 Å

PDB-7sot:
LaM domain of human LARP1 in complex with AAAAAA oligonucleotide
Method: X-RAY DIFFRACTION / Resolution: 1.52 Å

PDB-7sou:
LaM domain of human LARP1 in complex with AAAAAA polynucleotide
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

PDB-7sov:
LaM domain of human LARP1 in complex with AAAAAAAAAAA RNA polynucleotide
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsRNA BINDING PROTEIN / Winged helix fold / RNA binding domain / RNA BINDING PROTEIN/RNA / RNA BINDING PROTEIN-RNA complex

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