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TitleCleavage of mitochondrial homeostasis regulator PGAM5 by the intramembrane protease PARL is governed by transmembrane helix dynamics and oligomeric state.
Journal, issue, pagesJ. Biol. Chem., Vol. 298, Page 102321-102321, Year 2022
Publish dateNov 17, 2021 (structure data deposition date)
AuthorsSiebert, V. / Silber, M. / Heuten, E. / Muhle-Goll, C. / Lemberg, M.K.
External linksJ. Biol. Chem. / PubMed:35921890
MethodsNMR (solution)
Structure data

PDB-7qal:
Three-dimensional structure of the PGAM5 C12L mutant TMD
Method: SOLUTION NMR

PDB-7qam:
Three-dimensional structure of the PGAM5 WT TMD
Method: SOLUTION NMR

PDB-7qao:
Three-dimensional structure of the PGAM5 C12S mutant TMD
Method: SOLUTION NMR

PDB-7qap:
Three-dimensional structure of the PGAM5 G17L mutant TMD
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / PARL / MITOCHONDRIA

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