+Search query
-Structure paper
Title | A unique class of Zn 2+ -binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile. |
---|---|
Journal, issue, pages | Nat Commun, Vol. 13, Page 4370-4370, Year 2022 |
Publish date | Jul 8, 2021 (structure data deposition date) |
Authors | Sacco, M.D. / Wang, S. / Adapa, S.R. / Zhang, X. / Lewandowski, E.M. / Gongora, M.V. / Keramisanou, D. / Atlas, Z.D. / Townsend, J.A. / Gatdula, J.R. ...Sacco, M.D. / Wang, S. / Adapa, S.R. / Zhang, X. / Lewandowski, E.M. / Gongora, M.V. / Keramisanou, D. / Atlas, Z.D. / Townsend, J.A. / Gatdula, J.R. / Morgan, R.T. / Hammond, L.R. / Marty, M.T. / Wang, J. / Eswara, P.J. / Gelis, I. / Jiang, R.H.Y. / Sun, X. / Chen, Y. |
External links | Nat Commun / PubMed:35902581 |
Methods | X-ray diffraction |
Resolution | 2.2 - 3 Å |
Structure data | PDB-7rcw: PDB-7rcx: PDB-7rcy: PDB-7rcz: PDB-7rd0: |
Chemicals | ChemComp-PEG: ChemComp-ACT: ChemComp-GOL: ChemComp-ZZ7: ChemComp-ZN: ChemComp-HOH: ChemComp-SO4: ChemComp-RB6: ChemComp-EPE: ChemComp-POL: |
Source |
|
Keywords | PEPTIDE BINDING PROTEIN / Peptidoglycan / PBP / PBP2 / cell wall / transpeptidase / b-lactam / gram-positive / spore / sporulation |