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Structure paper

TitleCrystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation.
Journal, issue, pagesMol. Cell, Vol. 82, Page 3299-, Year 2022
Publish dateFeb 8, 2022 (structure data deposition date)
AuthorsMary, C. / Soflaee, M.H. / Kesavan, R. / Gelin, M. / Brown, H. / Zacharias, G. / Mathews, T.P. / Lemoff, A. / Lionne, C. / Labesse, G. / Hoxhaj, G.
External linksMol. Cell / PubMed:35868311
MethodsX-ray diffraction
Resolution2.29 - 3.33 Å
Structure data

PDB-7r4j:
Crystal structure of human mitochondrial NAD kinase
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

PDB-7r4k:
Crystal structure of human mitochondrial NAD kinase
Method: X-RAY DIFFRACTION / Resolution: 3.33 Å

PDB-7r4l:
Crystal structure of human mitochondrial NAD kinase
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-7r4m:
Crystal structure of mitochondrial NAD kinase
Method: X-RAY DIFFRACTION / Resolution: 2.29 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-FE:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Apo-form / NADP bound form with Magnesium / NADP bound form with iron / NAD kinase

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