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| Title | The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. |
|---|---|
| Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 119, Page e2200468119-e2200468119, Year 2022 |
| Publish date | Feb 23, 2021 (structure data deposition date) |
Authors | Guthertz, N. / van der Kant, R. / Martinez, R.M. / Xu, Y. / Trinh, C. / Iorga, B.I. / Rousseau, F. / Schymkowitz, J. / Brockwell, D.J. / Radford, S.E. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:35613051 |
| Methods | X-ray diffraction |
| Resolution | 1.15 - 1.51 Å |
| Structure data | ![]() PDB-7nmc: ![]() PDB-7nmo: ![]() PDB-7nmr: ![]() PDB-7nmt: ![]() PDB-7nmv: ![]() PDB-7nmy: ![]() PDB-7nn5: |
| Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-PGE: ![]() ChemComp-HOH: |
| Source |
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Keywords | IMMUNE SYSTEM / major histocompatibility complex class 1 / beta-2-microglobulin / mutant / D76E / D76A / D76S / D76G / D76Q / D76Y / D76K |
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homo sapiens (human)
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