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TitleSculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation.
Journal, issue, pagesBioconjug. Chem., Vol. 33, Page 1192-1200, Year 2022
Publish dateFeb 3, 2022 (structure data deposition date)
AuthorsHwang, D. / Nilchan, N. / Park, H. / Roy, R.N. / Roush, W.R. / Rader, C.
External linksBioconjug. Chem. / PubMed:35584359
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-7tus:
Sculpting a uniquely reactive cysteine residue for site-specific antibody conjugation
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Antibody therapeutics / antibody-drug conjugate / catalytic antibody / protein modification / engineered cysteine

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