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TitleDiscovery and Structural Basis of the Selectivity of Potent Cyclic Peptide Inhibitors of MAGE-A4.
Journal, issue, pagesJ. Med. Chem., Vol. 65, Page 7231-7245, Year 2022
Publish dateApr 12, 2022 (structure data deposition date)
AuthorsFleming, M.C. / Chiou, L.F. / Tumbale, P.P. / Droby, G.N. / Lim, J. / Norris-Drouin, J.L. / Williams, J.G. / Pearce, K.H. / Williams, R.S. / Vaziri, C. / Bowers, A.A.
External linksJ. Med. Chem. / PubMed:35522528
MethodsX-ray diffraction
Resolution3.5 Å
Structure data

PDB-7uoa:
MAGEA4-MTP1 linear peptide complex
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsPROTEIN BINDING / Mage homology domain MHD

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