タイトル | Structural and Thermodynamic Model for the Activation of Cardiac Troponin. |
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ジャーナル・号・ページ | Biochemistry, Vol. 61, Page 741-748, Year 2022 |
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掲載日 | 2021年11月17日 (構造データの登録日) |
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著者 | Poppe, L. / Hartman, J.J. / Romero, A. / Reagan, J.D. |
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リンク | Biochemistry / PubMed:35349258 |
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手法 | NMR (溶液) |
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構造データ | PDB-7sup: NMR structure of cTnC-TnI chimera bound to calcium and A1 手法: SOLUTION NMR PDB-7svc: NMR structure of cTnC-TnI chimera bound to calcium and A2 手法: SOLUTION NMR PDB-7swg: cTnC-TnI chimera complexed with A1 手法: SOLUTION NMR PDB-7swi: cTnC-TnI chimera complexed with A2 手法: SOLUTION NMR PDB-7sxc: cTnC-TnI chimera complexed with calcium 手法: SOLUTION NMR PDB-7sxd: NMR solution structure TnC-TnI chimera 手法: SOLUTION NMR |
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化合物 | ChemComp-BQ6: 4-(3-cyano-3-methylazetidine-1-carbonyl)-N-[(3S)-7-fluoro-6-methyl-3,4-dihydro-2H-1-benzopyran-3-yl]-5-methyl-1H-pyrrole-2-sulfonamide
ChemComp-C9W: 4-(3-cyano-3-methylazetidine-1-carbonyl)-N-[(3R,4S)-7-fluoro-4-hydroxy-6-methyl-3,4-dihydro-2H-1-benzopyran-3-yl]-5-methyl-1H-pyrrole-2-sulfonamide
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由来 | - homo sapiens (ヒト)
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キーワード | METAL BINDING PROTEIN / Calcium sensitizer / cardiac troponin / troponin activator |
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