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TitleStructural basis of R-loop recognition by the S9.6 monoclonal antibody.
Journal, issue, pagesNat Commun, Vol. 13, Page 1641-1641, Year 2022
Publish dateJan 26, 2022 (structure data deposition date)
AuthorsBou-Nader, C. / Bothra, A. / Garboczi, D.N. / Leppla, S.H. / Zhang, J.
External linksNat Commun / PubMed:35347133
MethodsX-ray diffraction
Resolution2.328 - 3.1 Å
Structure data

PDB-7tqa:
Crystal Structure of monoclonal S9.6 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.328 Å

PDB-7tqb:
Crystal structure of monoclonal S9.6 Fab bound to DNA-RNA hybrid
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / Antibody / Fab / DNA-RNA hybrid / Nucleic Acid binding protein / ribonucleoprotein complex / IMMUNE SYSTEM/DNA-RNA HYBRID / Antibody Fab DNA:RNA hybrid Nucleic Acid DNA:RNA hybrid binding protein / IMMUNE SYSTEM-DNA-RNA HYBRID complex

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