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TitleThe Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals.
Journal, issue, pagesViruses, Vol. 14, Year 2022
Publish dateJan 11, 2022 (structure data deposition date)
AuthorsWang, F. / Chen, C. / Wang, Z. / Han, X. / Shi, P. / Zhou, K. / Liu, X. / Xiao, Y. / Cai, Y. / Huang, J. ...Wang, F. / Chen, C. / Wang, Z. / Han, X. / Shi, P. / Zhou, K. / Liu, X. / Xiao, Y. / Cai, Y. / Huang, J. / Zhang, L. / Yang, H.
External linksViruses / PubMed:35336895
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-7wku:
Structure of PDCoV Mpro in complex with an inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • porcine deltacoronavirus
  • synthetic construct (others)
KeywordsVIRAL PROTEIN / virus / viral protease / drug design / inhibitor / broad-spectrum antivirals

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