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Structure paper

TitleStructures of RGL1 RAS-Association Domain in Complex with KRAS and the Oncogenic G12V Mutant.
Journal, issue, pagesJ. Mol. Biol., Vol. 434, Page 167527-167527, Year 2022
Publish dateSep 29, 2021 (structure data deposition date)
AuthorsEves, B.J. / Gebregiworgis, T. / Gasmi-Seabrook, G.M.C. / Kuntz, D.A. / Prive, G.G. / Marshall, C.B. / Ikura, M.
External linksJ. Mol. Biol. / PubMed:35257782
MethodsX-ray diffraction
Resolution1.96 - 1.98 Å
Structure data

PDB-7scw:
KRAS full length wild-type in complex with RGL1 Ras association domain
Method: X-RAY DIFFRACTION / Resolution: 1.98 Å

PDB-7scx:
KRAS full-length G12V in complex with RGL1 Ras association domain
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GSP:
5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

Source
  • homo sapiens (human)
KeywordsONCOPROTEIN / GTPase / RalGEF / Complex / Domain-swap

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