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Structure paper

TitleA strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties.
Journal, issue, pagesMabs, Vol. 14, Page 2044435-2044435, Year 2022
Publish dateNov 4, 2021 (structure data deposition date)
AuthorsZhao, J. / Jiang, L. / Yang, H. / Deng, L. / Meng, X. / Ding, J. / Yang, S. / Zhao, L. / Xu, W. / Wang, X. ...Zhao, J. / Jiang, L. / Yang, H. / Deng, L. / Meng, X. / Ding, J. / Yang, S. / Zhao, L. / Xu, W. / Wang, X. / Zhu, Z. / Huang, H.
External linksMabs / PubMed:35239451
MethodsX-ray diffraction
Resolution1.64 Å
Structure data

PDB-7vux:
Complex structure of PD1 and 609A-Fab
Method: X-RAY DIFFRACTION / Resolution: 1.64 Å

Chemicals

ChemComp-THR:
THREONINE

ChemComp-GOL:
GLYCEROL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-MG:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / PD1 Fab complex

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