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-Structure paper
Title | A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease. |
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Journal, issue, pages | Cell Chem Biol, Vol. 29, Page 947-957.e8, Year 2022 |
Publish date | Jan 11, 2021 (structure data deposition date) |
![]() | Douglas, L.E.J. / Reihill, J.A. / Ho, M.W.Y. / Axten, J.M. / Campobasso, N. / Schneck, J.L. / Rendina, A.R. / Wilcoxen, K.M. / Martin, S.L. |
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Methods | X-ray diffraction |
Resolution | 1.24 Å |
Structure data | ![]() PDB-7lcu: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-XTA: ![]() ChemComp-EDO: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/INHIBITOR / Inhibitor protease / HYDROLASE-INHIBITOR complex |