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TitleCrystal Structures of Botulinum Neurotoxin Subtypes A4 and A5 Cell Binding Domains in Complex with Receptor Ganglioside.
Journal, issue, pagesToxins, Vol. 14, Year 2022
Publish dateJan 5, 2022 (structure data deposition date)
AuthorsGregory, K.S. / Mojanaga, O.O. / Liu, S.M. / Acharya, K.R.
External linksToxins / PubMed:35202156
MethodsX-ray diffraction
Resolution2.3 - 2.4 Å
Structure data

PDB-7qpt:
Botulinum neurotoxin A4 cell binding domain in complex with GD1a oligosaccharide
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-7qpu:
Botulinum neurotoxin A5 cell binding domain in complex with GM1b oligosaccharide
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-SO4:
SULFATE ION

Source
  • clostridium botulinum (bacteria)
KeywordsTOXIN / Cell binding domain / receptor / oligosaccharide / neurotoxin

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