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TitleDesign of a Novel Fab-Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use.
Journal, issue, pagesSmall Methods, Vol. 6, Page e2100966-e2100966, Year 2022
Publish dateOct 27, 2021 (structure data deposition date)
AuthorsWang, C. / Hong, J. / Yang, Z. / Zhou, X. / Yang, Y. / Kong, Y. / Chen, B. / Wu, H. / Qian, B.Z. / Dimitrov, D.S. ...Wang, C. / Hong, J. / Yang, Z. / Zhou, X. / Yang, Y. / Kong, Y. / Chen, B. / Wu, H. / Qian, B.Z. / Dimitrov, D.S. / Wu, Y. / Ying, T.
External linksSmall Methods / PubMed:35174992
MethodsX-ray diffraction
Resolution3 - 3.1 Å
Structure data

PDB-7vsu:
Crystal structure of Fab fragment of anti-mesothelin antibody
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-7vsw:
Crystal structure of a Fab-like fragment of anti-mesothelin antibody
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Source
  • homo sapiens (human)
KeywordsBIOSYNTHETIC PROTEIN / antibody / therapeutic

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