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Structure paper

TitleStructural study of ponatinib in inhibiting SRC kinase.
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 598, Page 15-19, Year 2022
Publish dateDec 26, 2021 (structure data deposition date)
AuthorsGuo, M. / Duan, Y. / Dai, S. / Li, J. / Chen, X. / Qu, L. / Chen, Z. / Wei, H. / Jiang, L. / Chen, Y.
External linksBiochem. Biophys. Res. Commun. / PubMed:35151199
MethodsX-ray diffraction
Resolution1.798 Å
Structure data

PDB-7wf5:
c-Src in complex with ponatinib
Method: X-RAY DIFFRACTION / Resolution: 1.798 Å

Chemicals

ChemComp-0LI:
3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam / medication*YM

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
KeywordsONCOPROTEIN / Inhibitor / Kinase

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