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| Title | Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions. |
|---|---|
| Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 119, Year 2022 |
| Publish date | Nov 16, 2021 (structure data deposition date) |
Authors | Milder, F.J. / Jongeneelen, M. / Ritschel, T. / Bouchier, P. / Bisschop, I.J.M. / de Man, M. / Veldman, D. / Le, L. / Kaufmann, B. / Bakkers, M.J.G. ...Milder, F.J. / Jongeneelen, M. / Ritschel, T. / Bouchier, P. / Bisschop, I.J.M. / de Man, M. / Veldman, D. / Le, L. / Kaufmann, B. / Bakkers, M.J.G. / Juraszek, J. / Brandenburg, B. / Langedijk, J.P.M. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:35131851 |
| Methods | X-ray diffraction |
| Resolution | 2.19 Å |
| Structure data | ![]() PDB-7qa4: |
| Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-NO3: ![]() ChemComp-HOH: |
| Source |
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Keywords | VIRAL PROTEIN / Influenza / Hemagglutinin / Stabilized / Fusion protein / UNKNOWN FUNCTION |
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influenza a virus (strain a/hong kong/1/1968 h3n2)
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