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-Structure paper
Title | A glucose-based molecular rotor inhibitor of glycogen phosphorylase as a probe of cellular enzymatic function. |
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Journal, issue, pages | Org. Biomol. Chem., Vol. 20, Page 2407-2423, Year 2022 |
Publish date | Nov 3, 2021 (structure data deposition date) |
Authors | Minadakis, M.P. / Mavreas, K.F. / Neofytos, D.D. / Paschou, M. / Kogkaki, A. / Athanasiou, V. / Mamais, M. / Veclani, D. / Iatrou, H. / Venturini, A. ...Minadakis, M.P. / Mavreas, K.F. / Neofytos, D.D. / Paschou, M. / Kogkaki, A. / Athanasiou, V. / Mamais, M. / Veclani, D. / Iatrou, H. / Venturini, A. / Chrysina, E.D. / Papazafiri, P. / Gimisis, T. |
External links | Org. Biomol. Chem. / PubMed:35119451 |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | PDB-7q5i: |
Chemicals | ChemComp-I0F: ChemComp-CO3: ChemComp-BME: ChemComp-HOH: |
Source |
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Keywords | SUGAR BINDING PROTEIN / Glycogen phosphorylase / inhibitor / type 2 diabetes / molecular rotors |