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TitleDevelopment of a potent high-affinity human therapeutic antibody via novel application of recombination signal sequence-based affinity maturation.
Journal, issue, pagesJ. Biol. Chem., Vol. 298, Page 101533-101533, Year 2022
Publish dateJul 13, 2021 (structure data deposition date)
AuthorsKielczewska, A. / D'Angelo, I. / Amador, M.S. / Wang, T. / Sudom, A. / Min, X. / Rathanaswami, P. / Pigott, C. / Foltz, I.N.
External linksJ. Biol. Chem. / PubMed:34973336
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-7rew:
Crystal Structure of IL-13 in complex with MMAb3 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • macaca fascicularis (crab-eating macaque)
KeywordsCYTOKINE / alpha-helical bundle / protein-Fab complex

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