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-Structure paper
タイトル | Symmetry Reduction in a Hyperpolarization-Activated Homotetrameric Ion Channel. |
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ジャーナル・号・ページ | Biochemistry, Vol. 61, Issue 20, Page 2177-2181, Year 2022 |
掲載日 | 2021年12月29日 |
![]() | Miles Sasha Dickinson / Sergei Pourmal / Meghna Gupta / Maxine Bi / Robert M Stroud / ![]() |
PubMed 要旨 | Plants obtain nutrients from the soil via transmembrane transporters and channels in their root hairs, from which ions radially transport in toward the xylem for distribution across the plant body. ...Plants obtain nutrients from the soil via transmembrane transporters and channels in their root hairs, from which ions radially transport in toward the xylem for distribution across the plant body. We determined structures of the hyperpolarization-activated channel AKT1 from , which mediates K uptake from the soil into plant roots. These structures of AtAKT1 embedded in lipid nanodiscs show that the channel undergoes a reduction of C4 to C2 symmetry, possibly to regulate its electrical activation. |
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手法 | EM (単粒子) |
解像度 | 2.8 Å |
構造データ | EMDB-25691, PDB-7t4x: |
化合物 | ![]() ChemComp-K: ![]() ChemComp-PTY: ![]() ChemComp-HOH: |
由来 |
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![]() | MEMBRANE PROTEIN / K+ channel / ion channel / hyperpolarization-activated channel / voltage-gated channel |