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Structure paper

TitleMolecular architecture of the human tRNA ligase complex.
Journal, issue, pagesElife, Vol. 10, Year 2021
Publish dateJul 7, 2021 (structure data deposition date)
AuthorsKroupova, A. / Ackle, F. / Asanovic, I. / Weitzer, S. / Boneberg, F.M. / Faini, M. / Leitner, A. / Chui, A. / Aebersold, R. / Martinez, J. / Jinek, M.
External linksElife / PubMed:34854379
MethodsX-ray diffraction
Resolution2 - 2.3 Å
Structure data

PDB-7p3a:
N-terminal domain of CGI-99
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-7p3b:
Human RNA ligase RTCB in complex with GMP and Co(II)
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-5GP:
GUANOSINE-5'-MONOPHOSPHATE

ChemComp-CO:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-FMT:
FORMIC ACID

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsUNKNOWN FUNCTION / calponin homology domain / hCLE / RTRAF / c14orf166 / LIGASE / tRNA splicing ligase / HSPC117 / 3'-phosphate/5'-hydroxy nucleic acid ligase

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