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TitleRecognition of the antigen-presenting molecule MR1 by a V delta 3 + gamma delta T cell receptor.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 118, Year 2021
Publish dateFeb 4, 2021 (structure data deposition date)
AuthorsRice, M.T. / von Borstel, A. / Chevour, P. / Awad, W. / Howson, L.J. / Littler, D.R. / Gherardin, N.A. / Le Nours, J. / Giles, E.M. / Berry, R. ...Rice, M.T. / von Borstel, A. / Chevour, P. / Awad, W. / Howson, L.J. / Littler, D.R. / Gherardin, N.A. / Le Nours, J. / Giles, E.M. / Berry, R. / Godfrey, D.I. / Davey, M.S. / Rossjohn, J. / Gully, B.S.
External linksProc. Natl. Acad. Sci. USA / PubMed:34845016
MethodsX-ray diffraction
Resolution3.15 - 3.2 Å
Structure data

PDB-7lli:
Stimulatory immune receptor protein complex
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-7llj:
Inhibitory immune receptor protein complex
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

Chemicals

ChemComp-2LJ:
1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol

ChemComp-30W:
N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Immune receptor complex / metabolite immunity

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