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Structure paper

TitleCrystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site.
Journal, issue, pagesStructure, Vol. 30, Page 206-214.e4, Year 2022
Publish dateJul 9, 2021 (structure data deposition date)
AuthorsLipper, C.H. / Gabriel, K.H. / Seegar, T.C.M. / Durr, K.L. / Tomlinson, M.G. / Blacklow, S.C.
External linksStructure / PubMed:34739841
MethodsX-ray diffraction
Resolution2.52 - 3.6 Å
Structure data

PDB-7rd5:
Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL) in complex with 1C12 Fab
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

PDB-7rdb:
Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL)
Method: X-RAY DIFFRACTION / Resolution: 2.52 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsCELL ADHESION / Tetraspanin / Membrane Protein / Protein Trafficking

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