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TitleInhibiting parasite proliferation using a rationally designed anti-tubulin agent.
Journal, issue, pagesEmbo Mol Med, Vol. 13, Page e13818-e13818, Year 2021
Publish dateAug 24, 2021 (structure data deposition date)
AuthorsGaillard, N. / Sharma, A. / Abbaali, I. / Liu, T. / Shilliday, F. / Cook, A.D. / Ehrhard, V. / Bangera, M. / Roberts, A.J. / Moores, C.A. ...Gaillard, N. / Sharma, A. / Abbaali, I. / Liu, T. / Shilliday, F. / Cook, A.D. / Ehrhard, V. / Bangera, M. / Roberts, A.J. / Moores, C.A. / Morrissette, N. / Steinmetz, M.O.
External linksEmbo Mol Med / PubMed:34661376
MethodsX-ray diffraction
Resolution1.75 - 1.862 Å
Structure data

PDB-7pje:
Inhibiting parasite proliferation using a rationally designed anti-tubulin agent
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-7pjf:
Inhibiting parasite proliferation using a rationally designed anti-tubulin agent
Method: X-RAY DIFFRACTION / Resolution: 1.862 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
  • tetrahymena thermophila (eukaryote)
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / Tubulin / Microtubules / Protozoa / Apicomplexa

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