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TitleSystematic Evaluation of Fluorination as Modification for Peptide-Based Fusion Inhibitors against HIV-1 Infection.
Journal, issue, pagesChembiochem, Vol. 22, Page 3443-3451, Year 2021
Publish dateJan 10, 2020 (structure data deposition date)
AuthorsHuhmann, S. / Nyakatura, E.K. / Rohrhofer, A. / Moschner, J. / Schmidt, B. / Eichler, J. / Roth, C. / Koksch, B.
External linksChembiochem / PubMed:34605595
MethodsX-ray diffraction
Resolution1.25 - 1.45 Å
Structure data

PDB-6tvq:
Structure of native gp41 derived peptide fusion inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

PDB-6tvu:
Structure of native gp41 derived peptide fusion inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.25 Å

PDB-6tvw:
Structure of native gp41 derived peptide fusion inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
KeywordsVIRAL PROTEIN / Inhibitor / helix bundle / HIV

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