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Structure paper

TitleAntibody blockade of CD96 by distinct molecular mechanisms.
Journal, issue, pagesMabs, Vol. 13, Page 1979800-1979800, Year 2021
Publish dateAug 31, 2021 (structure data deposition date)
AuthorsLee, P.S. / Chau, B. / Barman, I. / Bee, C. / Jashnani, A. / Hogan, J.M. / Aguilar, B. / Dollinger, G. / Rajpal, A. / Strop, P.
External linksMabs / PubMed:34595996
MethodsX-ray diffraction
Resolution2.12 - 2.58 Å
Structure data

PDB-7s11:
Crystal structure of Fab in complex with mouse CD96 monomer
Method: X-RAY DIFFRACTION / Resolution: 2.58 Å

PDB-7s13:
Crystal structure of Fab in complex with mouse CD96 dimer
Method: X-RAY DIFFRACTION / Resolution: 2.12 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-FLC:
CITRATE ANION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • rattus (rats)
KeywordsIMMUNE SYSTEM / Immunoglobulin / checkpoint / antibody / complex

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