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Structure paper

TitleStructural basis for human ZBTB7A action at the fetal globin promoter.
Journal, issue, pagesCell Rep, Vol. 36, Page 109759-109759, Year 2021
Publish dateMay 31, 2021 (structure data deposition date)
AuthorsYang, Y. / Ren, R. / Ly, L.C. / Horton, J.R. / Li, F. / Quinlan, K.G.R. / Crossley, M. / Shi, Y. / Cheng, X.
External linksCell Rep / PubMed:34592153
MethodsX-ray diffraction
Resolution2.401 - 2.9 Å
Structure data

PDB-7eyi:
Crystal structure of ZBTB7A in complex with gamma-globin -200 sequence element with C-194A mutation
Method: X-RAY DIFFRACTION / Resolution: 2.401 Å

PDB-7n5s:
ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 6)
Method: X-RAY DIFFRACTION / Resolution: 2.86 Å

PDB-7n5t:
ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 5)
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-BO3:
BORIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / ZBTB7A / gamma-globin / -200 cluste. / DNA BINDING PROTEIN/DNA / Z=zinc-finger domain / gene expression / DNA BINDING PROTEIN-DNA complex

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