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TitleStructural basis for UFM1 transfer from UBA5 to UFC1.
Journal, issue, pagesNat Commun, Vol. 12, Page 5708-5708, Year 2021
Publish dateMar 15, 2021 (structure data deposition date)
AuthorsKumar, M. / Padala, P. / Fahoum, J. / Hassouna, F. / Tsaban, T. / Zoltsman, G. / Banerjee, S. / Cohen-Kfir, E. / Dessau, M. / Rosenzweig, R. ...Kumar, M. / Padala, P. / Fahoum, J. / Hassouna, F. / Tsaban, T. / Zoltsman, G. / Banerjee, S. / Cohen-Kfir, E. / Dessau, M. / Rosenzweig, R. / Isupov, M.N. / Schueler-Furman, O. / Wiener, R.
External linksNat Commun / PubMed:34588452
MethodsX-ray diffraction
Resolution1.95 - 2.651 Å
Structure data

PDB-7nvj:
Crystal structure of UFC1 Y110A & F121A
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-7nvk:
Crystal structure of UBA5 fragment fused to the N-terminus of UFC1
Method: X-RAY DIFFRACTION / Resolution: 2.651 Å

PDB-7nw1:
Crystal structure of UFC1 in complex with UBA5
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-PGE:
TRIETHYLENE GLYCOL

Source
  • homo sapiens (human)
KeywordsLIGASE / Ubiquitin fold conjugating enzyme 1 (UFC1) / Ufmylation / Y110A / F121A / Ubiquitin like fold modifier enzyme 5 (UBA5) / E1 / Ubiquitin fold modifier 1 (UFM1) / Ubiquitin fold modifier conjugating enzyme 1 (UFC1) / Ubiquitin fold modifier conjugating enzyme2 (UFC1)

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