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Structure paper

TitleStructural insights into hepatitis C virus receptor binding and entry.
Journal, issue, pagesNature, Vol. 598, Page 521-525, Year 2021
Publish dateMay 17, 2021 (structure data deposition date)
AuthorsKumar, A. / Hossain, R.A. / Yost, S.A. / Bu, W. / Wang, Y. / Dearborn, A.D. / Grakoui, A. / Cohen, J.I. / Marcotrigiano, J.
External linksNature / PubMed:34526719
MethodsX-ray diffraction
Resolution1.8 - 3.32 Å
Structure data

PDB-7mws:
Crystal structure of tamarin CD81 large extracellular loop
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-7mww:
Structure of hepatitis C virus envelope full-length glycoprotein 2 (eE2) from J6 genotype
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

PDB-7mwx:
Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 with tamarin CD81
Method: X-RAY DIFFRACTION / Resolution: 3.32 Å

Chemicals

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • saguinus oedipus (cotton-top tamarin)
  • hepacivirus c
  • mus musculus (house mouse)
KeywordsSTRUCTURAL PROTEIN / Receptor protein / PROTEIN BINDING / VIRAL PROTEIN/IMMUNE SYSTEM / Glycoprotein / Viral protein / VIRAL PROTEIN-IMMUNE SYSTEM complex / Receptor

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