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Structure paper

TitleStructural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase.
Journal, issue, pagesChembiochem, Vol. 22, Page 3060-3066, Year 2021
Publish dateMay 21, 2021 (structure data deposition date)
AuthorsKropp, H.M. / Ludmann, S. / Diederichs, K. / Betz, K. / Marx, A.
External linksChembiochem / PubMed:34486208
MethodsX-ray diffraction
Resolution1.92 - 2.1 Å
Structure data

PDB-7om3:
Crystal structure of KOD DNA Polymerase in a binary complex with Hypoxanthine containing template
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

PDB-7omb:
Crystal structure of KOD DNA Polymerase in a ternary complex with a p/t duplex containing an extended 5' single stranded template overhang
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

PDB-7omg:
Crystal structure of KOD DNA Polymerase in a ternary complex with an Uracil containing template
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-BR:
BROMIDE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-DTP:
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-MN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

Source
  • thermococcus kodakarensis kod1 (archaea)
  • synthetic construct (others)
KeywordsREPLICATION / Hypoxanthine / binary complex / DNA polymerase / ternary complex / uracil

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