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Structure paper

TitleStructural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element.
Journal, issue, pagesNucleic Acids Res., Vol. 49, Page 8923-8933, Year 2021
Publish dateMay 28, 2020 (structure data deposition date)
AuthorsLiu, X. / Weikum, E.R. / Tilo, D. / Vinson, C. / Ortlund, E.A.
External linksNucleic Acids Res. / PubMed:34289059
MethodsX-ray diffraction
Resolution2 - 2.48 Å
Structure data

PDB-6x6d:
Glucocorticoid Receptor DNA binding domain in complex with unmodified precursor for a modern recognition element (pre-GBS)
Method: X-RAY DIFFRACTION / Resolution: 2.48 Å

PDB-6x6e:
Glucocorticoid Receptor DNA binding domain in complex with methylated precursor for a modern recognition element (methylated pre-GBS)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CAC:
CACODYLATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA/DNA BINDING PROTEIN / GR / pre-GBS / DNA BINDING PROTEIN / DNA-DNA BINDING PROTEIN complex

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