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-Structure paper
| Title | Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer. |
|---|---|
| Journal, issue, pages | Sci Transl Med, Vol. 13, Year 2021 |
| Publish date | Apr 4, 2018 (structure data deposition date) |
 Authors | Chrysostomou, S. / Roy, R. / Prischi, F. / Thamlikitkul, L. / Chapman, K.L. / Mufti, U. / Peach, R. / Ding, L. / Hancock, D. / Moore, C. ...Chrysostomou, S. / Roy, R. / Prischi, F. / Thamlikitkul, L. / Chapman, K.L. / Mufti, U. / Peach, R. / Ding, L. / Hancock, D. / Moore, C. / Molina-Arcas, M. / Mauri, F. / Pinato, D.J. / Abrahams, J.M. / Ottaviani, S. / Castellano, L. / Giamas, G. / Pascoe, J. / Moonamale, D. / Pirrie, S. / Gaunt, C. / Billingham, L. / Steven, N.M. / Cullen, M. / Hrouda, D. / Winkler, M. / Post, J. / Cohen, P. / Salpeter, S.J. / Bar, V. / Zundelevich, A. / Golan, S. / Leibovici, D. / Lara, R. / Klug, D.R. / Yaliraki, S.N. / Barahona, M. / Wang, Y. / Downward, J. / Skehel, J.M. / Ali, M.M.U. / Seckl, M.J. / Pardo, O.E. |
 External links | Sci Transl Med / PubMed:34261798 |
| Methods | X-ray diffraction |
| Resolution | 2.499 - 3 Å |
| Structure data |  PDB-6g76:  PDB-6g77:  PDB-6g78: |
| Chemicals |  ChemComp-ANP:  ChemComp-ZN:  ChemComp-HOH: |
| Source |
|
 Keywords | TRANSFERASE / RSK4 / AGC kinase / p90 ribosomal S6 kinases |
homo sapiens (human)