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Structure paper

TitleStructural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6.
Journal, issue, pagesMaterials, Vol. 14, Year 2021
Publish dateOct 11, 2019 (structure data deposition date)
AuthorsBujacz, A. / Rum, J. / Rutkiewicz, M. / Pietrzyk-Brzezinska, A.J. / Bujacz, G.
External linksMaterials / PubMed:34204354
MethodsX-ray diffraction
Resolution1.62 - 2.59 Å
Structure data

PDB-6t3v:
Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - malic acid
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

PDB-6zup:
Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - L-(-)-3-phenyllactic acid
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-6zur:
Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - L-p-hydroxyphenyllactic acid
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

PDB-6zvg:
Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - L-indole-3-lactic acid
Method: X-RAY DIFFRACTION / Resolution: 2.59 Å

Chemicals

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-LMR:
(2S)-2-hydroxybutanedioic acid

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-NO3:
NITRATE ION

ChemComp-HFA:
ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID

ChemComp-TYF:
(2S)-2-hydroxy-3-(4-hydroxyphenyl)propanoic acid

ChemComp-3IL:
3-(INDOL-3-YL) LACTATE

Source
  • psychrobacter sp. b6 (bacteria)
KeywordsTRANSFERASE / psychrophilic / aminotranasferase / cold-adapted / enzyme / complex / malic acid / inhibitor / phenyllactic acid / hydroxyphenyllactic acid / indole-3-lactic acid

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