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TitleCrystal structure of an apo 7 alpha-hydroxysteroid dehydrogenase reveals key structural changes induced by substrate and co-factor binding.
Journal, issue, pagesJ. Steroid Biochem. Mol. Biol., Vol. 212, Page 105945-105945, Year 2021
Publish dateApr 21, 2021 (structure data deposition date)
AuthorsKim, K.H. / Lee, C.W. / Pardhe, B.D. / Hwang, J. / Do, H. / Lee, Y.M. / Lee, J.H. / Oh, T.J.
External linksJ. Steroid Biochem. Mol. Biol. / PubMed:34171491
MethodsX-ray diffraction
Resolution2.703 Å
Structure data

PDB-7eny:
Crystal structure of hydroxysteroid dehydrogenase from Escherichia coli
Method: X-RAY DIFFRACTION / Resolution: 2.703 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • escherichia coli k-12 (bacteria)
KeywordsHYDROLASE / ketolithocholic acid / alcohol dehydrogenase / hydroxysteroid dehydrogenase / ursodeoxycholic acid

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