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TitleA Standalone beta-Ketoreductase Acts Concomitantly with Biosynthesis of the Antimycin Scaffold.
Journal, issue, pagesAcs Chem. Biol., Vol. 16, Page 1152-1158, Year 2021
Publish dateFeb 23, 2021 (structure data deposition date)
AuthorsFazal, A. / Hemsworth, G.R. / Webb, M.E. / Seipke, R.F.
External linksAcs Chem. Biol. / PubMed:34151573
MethodsX-ray diffraction
Resolution1.7 - 2.1 Å
Structure data

PDB-7nm7:
The crystal structure of the antimycin pathway standalone ketoreductase, AntM
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-7nm8:
The crystal structure of the antimycin pathway standalone ketoreductase, AntM, in complex with NADPH
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-GOL:
GLYCEROL

Source
  • streptomyces albus (bacteria)
KeywordsOXIDOREDUCTASE / Ketoreductase / Standalone / Antimycin / Polyketide / NADPH

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