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Structure paper

TitleClostridioides difficile specific DNA adenine methyltransferase CamA squeezes and flips adenine out of DNA helix.
Journal, issue, pagesNat Commun, Vol. 12, Page 3436-3436, Year 2021
Publish dateFeb 7, 2021 (structure data deposition date)
AuthorsZhou, J. / Horton, J.R. / Blumenthal, R.M. / Zhang, X. / Cheng, X.
External linksNat Commun / PubMed:34103525
MethodsX-ray diffraction
Resolution2.54 - 2.68 Å
Structure data

PDB-7lni:
SeMet CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA
Method: X-RAY DIFFRACTION / Resolution: 2.68 Å

PDB-7lnj:
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA
Method: X-RAY DIFFRACTION / Resolution: 2.68 Å

PDB-7lt5:
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Cofactor SAH
Method: X-RAY DIFFRACTION / Resolution: 2.54 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

Source
  • clostridioides difficile (bacteria)
  • synthetic construct (others)
KeywordsTRANSFERASE/DNA / DNA Adenine Methylation / PROTEIN-DNA COMPLEX / TRANSFERASE / TRANSFERASE-DNA complex

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