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Structure paper

TitleCIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
Journal, issue, pagesNeuron, Vol. 109, Page 2131-2149.e15, Year 2021
Publish dateMay 4, 2020 (structure data deposition date)
AuthorsLiang, X. / Qiu, X. / Dionne, G. / Cunningham, C.L. / Pucak, M.L. / Peng, G. / Kim, Y.H. / Lauer, A. / Shapiro, L. / Muller, U.
External linksNeuron / PubMed:34089643
MethodsX-ray diffraction
Resolution1.84 - 1.88 Å
Structure data

PDB-6wu5:
Human Calcium and Integrin Binding Protein 3
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

PDB-6wu7:
Human Calcium and Integrin Binding Protein 3 E150Q K151H
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

PDB-6wud:
Human Calcium and Integrin Binding Protein 3 Bound to TMC1 Residues 303-347
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-SCN:
THIOCYANATE ION

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsMETAL BINDING PROTEIN / EF-hand / Dimer / NCS / Mechanotransduction / hearing / METAL BINDING/TRANSPORT PROTEIN / METAL BINDING-TRANSPORT PROTEIN complex

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