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TitleCrystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist.
Journal, issue, pagesNat Commun, Vol. 12, Page 3305-3305, Year 2021
Publish dateAug 7, 2020 (structure data deposition date)
AuthorsSun, B. / Feng, D. / Chu, M.L. / Fish, I. / Lovera, S. / Sands, Z.A. / Kelm, S. / Valade, A. / Wood, M. / Ceska, T. ...Sun, B. / Feng, D. / Chu, M.L. / Fish, I. / Lovera, S. / Sands, Z.A. / Kelm, S. / Valade, A. / Wood, M. / Ceska, T. / Kobilka, T.S. / Lebon, F. / Kobilka, B.K.
External linksNat Commun / PubMed:34083522
MethodsX-ray diffraction
Resolution3.8 Å
Structure data

PDB-7joz:
Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist
Method: X-RAY DIFFRACTION / Resolution: 3.8 Å

Chemicals

ChemComp-VFP:
6-{4-[(furo[3,2-c]pyridin-4-yl)oxy]-2-methylphenyl}-1,5-dimethylpyrimidine-2,4(1H,3H)-dione

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

Source
  • homo sapiens (human)
  • lama glama (llama)
  • enterobacteria phage t4 (virus)
KeywordsMEMBRANE PROTEIN / Dopamine receptor / D1 / non-catechol agonist / G protein

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