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Structure paper

TitleThe impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 77, Page 854-866, Year 2021
Publish dateFeb 4, 2021 (structure data deposition date)
AuthorsSalinas-Garcia, M.C. / Plaza-Garrido, M. / Camara-Artigas, A.
External linksActa Crystallogr D Struct Biol / PubMed:34076598
MethodsX-ray diffraction
Resolution1.35 - 1.55 Å
Structure data

PDB-7ner:
Crystal structure of the v-Src SH3 domain Q128R mutant
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-7nes:
Crystal structure of the v-Src SH3 domain N117D-V124L mutant
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-7net:
Crystal structure of the v-Src SH3 domain W95R-I96T mutant
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-GLY:
GLYCINE

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-PGE:
TRIETHYLENE GLYCOL

Source
  • gallus gallus (chicken)
KeywordsPROTEIN BINDING / beta barrel / SH3 domain

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