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TitleSingle-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines.
Journal, issue, pagesNat Commun, Vol. 12, Page 2633-2633, Year 2021
Publish dateAug 8, 2020 (structure data deposition date)
AuthorsHe, L. / Chaudhary, A. / Lin, X. / Sou, C. / Alkutkar, T. / Kumar, S. / Ngo, T. / Kosviner, E. / Ozorowski, G. / Stanfield, R.L. ...He, L. / Chaudhary, A. / Lin, X. / Sou, C. / Alkutkar, T. / Kumar, S. / Ngo, T. / Kosviner, E. / Ozorowski, G. / Stanfield, R.L. / Ward, A.B. / Wilson, I.A. / Zhu, J.
External linksNat Commun / PubMed:33976149
MethodsX-ray diffraction
Resolution2.28 - 3.195 Å
Structure data

PDB-7jph:
Crystal structure of EBOV glycoprotein with modified HR1c and HR2 stalk at 3.2 A resolution
Method: X-RAY DIFFRACTION / Resolution: 3.195 Å

PDB-7jpi:
Crystal structure of EBOV glycoprotein with modified HR2 stalk at 2.3A resolution
Method: X-RAY DIFFRACTION / Resolution: 2.28 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-PO4:
PHOSPHATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • ebola virus - mayinga
  • zaire, 1976
KeywordsVIRAL PROTEIN / Ebola glycoprotein

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