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| Title | Structure of an ancestral ADP-dependent kinase with fructose-6P reveals key residues for binding, catalysis, and ligand-induced conformational changes. |
|---|---|
| Journal, issue, pages | J. Biol. Chem., Vol. 296, Page 100219-100219, Year 2020 |
| Publish date | Jun 20, 2020 (structure data deposition date) |
Authors | Munoz, S.M. / Castro-Fernandez, V. / Guixe, V. |
External links | J. Biol. Chem. / PubMed:33839685 |
| Methods | X-ray diffraction |
| Resolution | 3.12 Å |
| Structure data | ![]() PDB-6xio: |
| Chemicals | ![]() ChemComp-AT4: ![]() ChemComp-F6P: ![]() ChemComp-MG: ![]() ChemComp-HOH: |
| Source |
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Keywords | TRANSFERASE / ancestral protein reconstruction / ADP-dependent sugar kinases family / glucokinase / phosphofructokinase / enzyme evolution |
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methanosarcinales archaeon (archaea)
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