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TitleBroadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses.
Journal, issue, pagesJ. Exp. Med., Vol. 218, Year 2021
Publish dateDec 8, 2020 (structure data deposition date)
AuthorsVanBlargan, L.A. / Errico, J.M. / Kafai, N.M. / Burgomaster, K.E. / Jethva, P.N. / Broeckel, R.M. / Meade-White, K. / Nelson, C.A. / Himansu, S. / Wang, D. ...VanBlargan, L.A. / Errico, J.M. / Kafai, N.M. / Burgomaster, K.E. / Jethva, P.N. / Broeckel, R.M. / Meade-White, K. / Nelson, C.A. / Himansu, S. / Wang, D. / Handley, S.A. / Gross, M.L. / Best, S.M. / Pierson, T.C. / Fremont, D.H. / Diamond, M.S.
External linksJ. Exp. Med. / PubMed:33831142
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-7kyl:
Powassan virus Envelope protein DIII in complex with neutralizing Fab POWV-80
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • powassan virus
  • mus musculus (house mouse)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / Neutralizing antibody / Tick-borne flavivirus / domain III / Structural Genomics / Center for Structural Genomics of Infectious Diseases / CSGID / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex

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