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Structure paper

TitleStructural basis for recruitment of the CHK1 DNA damage kinase by the CLASPIN scaffold protein.
Journal, issue, pagesStructure, Vol. 29, Page 531-, Year 2021
Publish dateOct 1, 2020 (structure data deposition date)
AuthorsDay, M. / Parry-Morris, S. / Houghton-Gisby, J. / Oliver, A.W. / Pearl, L.H.
External linksStructure / PubMed:33789090
MethodsX-ray diffraction
Resolution1.8 - 1.93 Å
Structure data

PDB-7akm:
Crystal structure of CHK1 kinase domain in complex with ATPyS
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

PDB-7ako:
Crystal structure of CHK1 kinase domain in complex with a CLASPIN phosphopeptide
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-AGS:
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER / ATP-gamma-S, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

ChemComp-STU:
STAUROSPORINE / anticancer, antifungal, antibiotic, alkaloid*YM

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsCELL CYCLE

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