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Structure paper

TitleCrystal structures of inhibitor complexes of M-PMV protease with visible flap loops.
Journal, issue, pagesProtein Sci., Vol. 30, Page 1258-1263, Year 2021
Publish dateJan 8, 2021 (structure data deposition date)
AuthorsWosicki, S. / Kazmierczyk, M. / Gilski, M. / Zabranska, H. / Pichova, I. / Jaskolski, M.
External linksProtein Sci. / PubMed:33786913
MethodsX-ray diffraction
Resolution1.93 - 2.433 Å
Structure data

PDB-7bgt:
Mason-Pfizer Monkey Virus Protease mutant C7A/D26N/C106A in complex with peptidomimetic inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

PDB-7bgu:
Mason-Pfizer Monkey Virus Protease mutant C7A/D26N/C106A in complex with peptidomimetic inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.433 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • mason-pfizer monkey virus
  • synthetic construct (others)
KeywordsHYDROLASE / Mason-Pfizer Monkey Virus / M-PMV / retropepsin / active site inhibitor / active site mutant

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